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KMID : 1134820080370091120
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Journal of the Korean Society of Food Science and Nutrition
2008 Volume.37 No. 9 p.1120 ~ p.1125
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Effcts of Sophorae fructus on Antioxidative Activities and Lipid Levels in Rats
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Park Sung-Jin
Kim Eun-Sil
Kim Jong-Dai
Choi Young-Su
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Abstract
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This study was carried out to investigate the effects of Sophorae fructus extracts on antioxidative potential, free radical generation and the lipid levels in rats. Sprague-Dawley (SD) rats were divided into 2 groups of either AIN-76 diet (control group) or modified AIN-76 diet with 0.5% Sophorae fructus extracts for 4 weeks. The result were as follows: body weight gain and feed efficiency ratios were not significantly different in both groups. Antioxidative potentials were significantly increased in the group fed Sophorae fructus extracts compared to control group; however, there was no difference in free radical generation. Organ (heart, kidney, liver, spleen) weights in rats were not different in both groups. Total cholesterol level in Sophorae fructus group was significantly decreased compared to control group. Serum HDL-cholesterol level in Sophorae fructus group was significantly higher than control group. Serum phospholipid and triglyceride contents in Sophorae fructus group were no different from control group. These results suggest that supplementation of Sophorae fructus extracts may beneficially contribute to the effects of antioxidative potential and lipid levels in rats.
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KEYWORD
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Sophorae fructus, total cholesterol, HDL-cholesterol, triglyceride, antioxidative activities
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